Human CD Chart



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Human CD & Other Cellular Antigens

Antibodies for multicolor flow cytometry, functional assays and immunohistochemistry

eBioscience human antibodies are available conjugated to a variety of fluorophores to enable multicolor flow cytometry, functional assays, and immunohistochemistry applications. Additional antibodies to other human antigens including novel cell surface molecules are in our pipeline.

Human CD Cellular Antigens

MW Structure Distribution Function eBioscience
CD1a T6 49kD IgSF, MHC-like cortical thymocytes, Langerhans cells, DC antigen presentation, with beta2m HI149
CD1b T6 45kD IgSF, MHC-like cortical thymocytes, Langerhans cells, DC antigen presentation, with beta2m eBioSN13
CD1c T6 43kD IgSF, MHC-like cortical thymocytes, Langerhans cells, DC, B subset antigen presentation, with beta2m
CD1d 49kD IgSF, MHC-like intestinal epith, B subset, monolow, DC antigen presentation, with beta2m
CD1e 28kD IgSF, MHC-like DC antigen presentation, with beta2m
CD2 T11, LFA-2, SRBC-R 50kD IgSF thymocytes, T, NK CD58 ligand, adhesion, T cell activation RPA-2.10
CD2R T11-3 50kD IgSF Tact activation-dependent form of CD2
CD3 gamma, CD3 delta T3 IgSF T, thymocyte subset with TCR, TCR surface expression / signal transduction
CD3 epsilon T3 20kD IgSF T, thymocyte subset with TCR, TCR surface expression / signal transduction OKT3
CD4 T4 55kD IgSF thymocyte subset, T subset, mono, mac MHC class II coreceptor, HIV receptor, T cell differentiation / activation RPA-T4
CD5 T1, Tp67 67kD Scavenger R SF thymocytes, T, B subset, B-CLL CD72 receptor, TCR or BCR signaling, T-B interaction UCHT2
CD6 T12 100-130kD Scavenger R SF thymocytes, T, B subset CD166 receptor, T cell differentiation / costimulation
CD7 40kD IgSF hematopoietic progenitors, thymocytes, T, NK T costimulation CD7-6B7
CD8a T8, Leu-2 32-34kD IgSF thymocyte subset, T subset, NK MHC class I coreceptor, receptor for some mutated HIV-1, T cell differentiation / activation RPA-T8
CD8b 30-32kD IgSF thymocyte subset, T subset
CD9 p24, MRP-1 22-27kD TM4SF pre-B, eosinophils, basophils, platelets, Tact cellular adhesion and migration eBioSN4 (SN4 C3-3A2)
CD10 CALLA, NEP, gp100 100kD type II TM B precursors, T precursors, neutrophils zinc-binding metalloproteinase, B cell development eBioCB-CALLA (CB-CALLA)
CD11a LFA-1, integrin alphaL 180kD Integrin family lymph, gran, mono, mac CD11a / CD18 receptor for ICAM-1, -2,-3, intercellular adhesion, T costimulation HI111
CD11b Mac-1, integrin alphaM 170kD Integrin family myeloid cells, NK binds CD54, ECM, iC3b CBRM1/5
CD11c p150, 95, CR4, integrin alphaX 150kD Integrin family DC, myeloid cells, NK, B, T subset binds CD54, fibrinogen and iC3b 3.9
CD12 90-120kD mono, gran, platelets
CD13 Aminopeptidase N, APN 150-170kD type II TM myeloid cells zinc-binding metalloproteinase, antigen processing, receptor for corona virus strains WM-15
CD14 LPS-R 53-55kD GPI-linked mono, mac, Langerhans cells, granlow receptor for LPS/LBP, LPS recognition 61D3
CD15 Lewis-x, Lex CHO neutrophils, eosinophils, mono adhesion HI98
CD15s Sialyl Lewis X CHO neutrophils, eosinophils, mono, memory helper T, Tact and B, NK, HEV CD62L and CD62P ligand, adhesion
CD15u Sulfated Lewis X CHO myeloid subset adhesion
CD16a FcgammaRIIIA 50-65kD IgSF neutrophils, mac, NK component of low affinity Fc receptor, phagocytosis and ADCC eBioCB16 (CB16)
CD16b FcgammaRIIIB 48kD IgSF neutrophils component of low affinity Fc receptor, phagocytosis and ADCC
CD17 neutrophils, mono, platelets lactosyl ceramide
CD18 Integrin beta2 95kD Integrin family broad, all leukocytes with CD11a, b & c, adhesion CLB-LFA-1/1
CD19 B4 95kD IgSF B, FDC complex with CD21 and CD81, BCR coreceptor, B cell activation / differentiation HIB19
CD20 B1, Bp35 33-37kD TM4SF B, T subset B cell activation 2H7
CD21 C3DR, CR2, EBV-R 145,110kD CCRSF B, FDC, T subset complement C3d and EBV receptor, complex with CD19 and CD81, BCR coreceptor BU32
CD22 BL-CAM, Siglec-2 150kD IgSF, sialoadhesins B adhesion, B-mono, B-T interactions eBio4KB128
CD23 FcepsilonRII 45kD C-type lectin B, activated mac, eosinophils, FDC, platelets CD19-CD21-CD81 receptor, IgE low affinity receptor, signal transduction EBVCS2
CD24 BA-1 35-45kD GPI-linked thymocytes, erythrocytes, peripheral lymph, myeloid binds P-selectin eBioSN3 (SN3 A5-2H10)
CD25 Tac, p55 55kD type I TM Tact, Bact, lymph progenitors IL-2Ralpha, with IL-2Rbeta and gamma to form high affinity complex BC96
CD26 DPP IV 110kD type II TM thymocyte subset, Tact, soluble form dipeptidyl peptidase, T costimulation, HIV entry 2A6
CD27 T14 50-55kD TNFRSF medullary thymocytes, T, B subset, NK subset CD70 receptor, T costimulation O323
CD28 Tp44, T44 44kD IgSF most T, thymocytes, plasma cells CD80, CD86 receptor, T costimulation CD28.2
CD29 Integrin beta1 130kD Integrin family lymph, mono, granlow, platelets, mast cells, fibroblasts, endoth with CD49a (VLA-1) receptor for VCAM-1, MAdCAM-1 and ECM MEM-101A
CD30 Ki-1 105-120kD TNFRSF Bact, T and NK , Reed-Sternberg cells, anaplastic large cell lymphoma CD153 receptor, lymph proliferation / apoptosis
CD31 PECAM-1 130-140kD IgSF mono, platelets, gran, endoth, lymph subset CD38 receptor, adhesion WM59
CD32 FcgammaRII 40kD IgSF mono, gran, B, platelets low affinity Fc receptor for aggregated Ig and immune complexes
CD33 p67, Siglec-3 67kD IgSF, sialoadhesins myeloid progenitors, mono, gran, DC, mast cells, Tact adhesion HIM3-4
CD34 105-120kD Sialomucin, type I TM hematopoietic precursors, capillary endoth, embryonic fibroblasts stem cell marker, adhesion, CD62L receptor
CD35 CR1 250kD CCRSF erythrocytes, B, mono, neutrophils, eosinophils, FDC, T subset complement receptor 1, binds C3b and C4b, adhesion, phagocytosis
CD36 GPIV 88kD platelets, mono, mac, endoth, early erythrocytes ECM receptor, adhesion, phagocytosis mAb (please inquire)
CD37 40-52kD TM4SF B, Tlow, granlow signal transduction
CD38 T10 45kD variable levels on majority of hematopoietic cells, high expression on plasma cells, B and Tact ecto-ADP-ribosyl cyclase, cell activation HIT2
CD39 78kD NK, mac, Langerhans cells, DC, Bact B cell adhesion, protects activated cells from lysis, ecto-apyrase
CD40 48kD TNFRSF B, mono, mac, FDC, endoth, T subset CD154 receptor, B differentiation / costimulation, isotype-switching, rescues B cells from apoptosis 5C3
CD41 gpIIb 125/22kD Integrin family platelets, megakaryocytes with CD61 forms GPIIb, binds fibrinogen, fibronectin, vWF, thrombospondin, platelet activation and aggregation HIP2
CD42a GPIX 22kD LRRF platelets, megakaryocytes complex with CD42b, c and d, receptor for vWF and thrombin, platelet adhesion to subendothelial matrices
CD42b GPIba 145kD LRRF platelets, megakaryocytes complex with CD42a, c and d, binds to vWF and thrombin, platelet adhesion / activation HIP1
CD42c GPIbb 24kD LRRF platelets, megakaryocytes complex with CD42a, b, d
CD42d GPV 82kD LRRF platelets, megakaryocytes complex with CD42a-c
CD43 Leukosialin, sialophorin 115-135kD Sialomucin, type I TM leukocytes, except resting B, plateletslow inhibition of T cell interaction, CD54R, adhesion L10
CD44 H-CAM, Pgp-1 80-95kD hyaladherin family hematopoietic and non-hematopoietic cells, except platelets, hepatocytes, testis binds hyaluronic acid, adhesion IM7
CD44R CD44v CD44 variants heterogeneous expression, constitutively on epith, mono, upregulated on activated leukocytes adhesion, metastasis
CD45 LCA, T200, B220 180-240kD hematopoietic cells, multiple isoforms from alternative splicing tyrosine phosphatase, enhanced TCR & BCR signals HI30
CD45RA 205-220kD B, T subset(naive), mono exon A isoforms of CD45 HI100
CD45RB 190-220kD T subset, B, mono, mac, gran exon B isoforms of CD45 MEM-55
CD45RO 180kD Tact, memory T, B subset, mono, mac, gran isoform of CD45 lacking A, B, C exons UCHL1
CD46 MCP 56/66kD CCRSF nucleated cells membrane cofactor protein, binds C3b & C4b allowing degradation by Factor I, measles virus receptor
CD47 IAP 47-52kD IgSF hematopoietic cells, epith, endoth, fibroblasts, other tissues leukocyte adhesion, migration, activation
CD47R New designation for CDw149, similar distribution as CD47 but dimmer
CD48 Blast-1 45kD IgSF broad, all leukocytes cell adhesion
CD49a VLA-1 210kD Integrin family Tact, mono integrin alpha1, adhesion, CD49a/CD29 binds collagen and laminin
CD49b VLA-2 165kD Integrin family B, mono, platelets, Tact, megakaryocytes integrin alpha2, adhesion, CD49b / CD29 binds collagen and laminin eBioY418
CD49c VLA-3 125kD Integrin family B and Tlow, most adhesive cell lines integrin alpha3, adhesion, CD49c/CD29 binds laminin, fibronectin and collagen mAb (please inquire)
CD49d VLA-4 150kD Integrin family T, B, NK, thymocytes, mono, eosinophils, mast, DC integrin alpha4, adhesion, CD49d/CD29 binds fibronectin, VCAM-1 & MAdCAM-1 9F10
CD49e VLA-5 135, 25kD Integrin family thymocytes, T, mono, platelets, early and Bact integrin alpha5, adhesion, CD49e/CD29 binds fibronectin
CD49f VLA-6 125kD Integrin family memory T, thymocytes, mono, platelets, megakaryocytes, epith integrin alpha6, adhesion, CD49f / CD29 binds laminin
CD50 ICAM-3 110-120kD IgSF hematopoietic, endoth, epidermal Langerhans cells adhesion, costimulation TP1/25.1
CD51 Vitronectin receptor 125, 24kD Integrin family plateletslow, endoth, osteoblasts, melanomas integrin alphav, adhesion, CD51 / CD61 binds vitronectin, vWF, fibrinogen and thrombospondin 23C6
CD52 CAMPATH-1 21-28kD thymocytes, T, B (not plasma cells), mono, mac
CD53 35-42kD TM4SF leukocytes, DC, osteoblasts, osteoclasts signal transduction
CD54 ICAM-1 90-110kD IgSF endoth, mono, lymph (high upon activation) receptor for CD11a / CD18 (LFA-1), CD11b/CD18 (Mac-1) and rhinovirus HA58
CD55 DAF 60-70kD GPI-linked hematopoietic, endoth binds C3b, complement regulation 143-30
CD56 NCAM 175-185kD IgSF NK, T subset, neurons, some large granular lymphocyte leukemias, myeloid leukemias adhesion MEM188
CD57 HNK-1, Leu-7 110kD NK subset, T subset TB01
CD58 LFA-3 55-70kD IgSF hematopoietic, non-hematopoietic cells CD2 receptor, adhesion
CD59 Protectin, MAC- inhibitor 19kD GPI-linked hematopoietic, non-hematopoietic cells binds complement C8 and C9, blocks assembly of membrane attack complex MEM-43
CD60a GD3 CHO T subset, platelets, thymic epith, astrocytes costimulation
CD60b 9-O-sialyl GD3 CHO T subset, Bact
CD60c 7-O-sialyl GD3 CHO T subset
CD61 GPIIIa 105kD Integrin family platelets, megakaryocytes, mac, endoth integrin beta3, adhesion, CD41/CD61 or CD51 / CD61 mediate adhesion to ECM 23C6
CD62E E-selectin, ELAM-1 97,107-115kD Selectin family endoth binds CD15s, cell rolling, metastasis
CD62L L-selectin, LECAM-1 74, 95kD Selectin family B, naïve and memory T, mono, gran, NK, thymocytes CD34, GlyCAM, and MAdCAM-1 receptor, leukocyte homing, tethering, rolling Dreg56
CD62P P-selectin, PADGEM 140kD Selectin family activated platelets, endoth CD162, CD15s receptor, adhesion, neutrophil rolling, platelet-neutrophil and platelet-mono interactions AK-4
CD63 LIMP, LAMP-3 53kD TM4SF activated platelets, mono, mac lysosomal membrane protein, moves to cell surface after activation
CD64 FcgammaRI 72kD IgSF mono, mac, DC, Interferon or G-CSF activated gran high affinity receptor for IgG, phagocytosis and ADCC 10.1
CD65 gran, mono subset, myeloid leukemias
CD65s VIM2 gran, mono, myeloid leukemias phagocytosis
CD66a BGP-1, NCA-160 160-180kD IgSF, CEA family neutrophils, epith cell adhesion
CD66b CD67, CGM6 95-100kD IgSF, CEA family gran cell adhesion, neutrophil activation
CD66c NCA 90kD IgSF, CEA family neutrophils, colon carcinoma cell adhesion
CD66d CGM1 35kD IgSF, CEA family neutrophils
CD66e CEA 180-200kD IgSF, CEA family colon epith, colon cancer cell adhesion
CD66f PSG, Sp-1 54-72kD IgSF, CEA family pregnancy specific glycoprotein, placental syncytiotrophoblasts, fetal liver immune regulation, protects fetus from maternal immune system
CD68 Macrosialin, gp110 110kD Sialomucin intracellularly in mono, mac, neutrophils, basophils, large lymph, mast cells, DC, myeloid progenitors, liver eBioY1/82A
CD69 AIM 28, 32kD C-type lectin Tact, B, NK and gran, thymocytes, platelets, Langerhans cells signal transduction FN50
CD70 Ki-24 50, 70, 90, 160kD TNFSF Bact and Tact CD27 ligand, T and B cell costimulation
CD71 T9 95kD proliferating cells, reticulocytes, erythroid precursors transferrin receptor, iron uptake T56/14
CD72 Lyb-2 42kD C-type lectin B, FDC CD5, CD100 receptor, B proliferation
CD73 69kD GPI-linked B subset, T subset, FDC, epith ecto-5'-nucleotidase, nucleoside uptake, T costimulation, lymph adhesion
CD74 Ii, invariant chain 33, 35, 41, 43kD B, mac, mono, Langerhans cells, DC, Tact MHC class II traffic and function
CD75 CHO Sialoglycan family B subset, epith lactosamines
CD75s CHO Sialoglycan family B subset, T subset alpha-2,6-sialylated lactosamines (previously CDw75 and CDw76)
CD77 Gb3, Pk blood group germinal center B, Burkitt's lymphomashigh, follicular lymphomaslow apoptosis
CD79a Iga 33, 45kD IgSF B component of BCR, BCR surface expression and signal transduction
CD79b Igb 37kD IgSF B component of BCR, BCR surface expression and signal transduction SN8
CD80 B7, B7-1, BB1 60kD IgSF Bact and Tact, mac, DC binds to CD28, CD152, T costimulation 2D10.4
CD81 TAPA-1 26kD TM4SF T, B, NK, thymocytes, DC, endoth, fibroblast, neuroblastomas, melanomas complex with CD19 & CD21, signaling, T costimulation
CD82 R2 50-53kD TM4SF leukocytes signal transduction 53H5
CD83 HB15 43kD IgSF Bact and Tact, DC, Langerhans cells HB15e
CDw84 73kD mono, platelets, B, T subset, mac subset
CD85 110kD IgSF, ILT/LIR family DC, mono, B, NK, T subset inhibition of NK, T cell cytolytic function
CD86 B70, B7-2 80kD IgSF mono, DC, Bact and Tact binds to CD28, CD152, T costimulation IT2.2
CD87 UPA-R 39-66kD GPI-linked gran, mono, NK, Tact, endoth, fibroblasts urokinase plasminogen activator receptor, inflammatory cell invasion, metastasis
CD88 C5aR 40kD TM7SF gran, mono, DC C5a receptor, granulocyte activation
CD89 FcalphaR 55-75kD IgSF mono, mac, gran, neutrophils, B subset, T subset IgA receptor, phagocytosis, degranulation, respiratory burst
CD90 Thy-1 25-35kD IgSF, GPI-linked CD34+ hematopoietic subset, neurons hematopoietic stem cell and neuron differentiation
CD91 600kD LDLR family mono, mac, neurons, fibroblasts receptor for alpha-2-macroglobulin
CD92 70kD neutrophils, mono, platelets, endoth, fibroblasts
CD93 120kD neutrophils, mono, endoth mAb (please inquire)
CD94 KP43 43kD C-type lectin NK, T subset complex with NKG2, inhibits NK function DX22
CD95 Apo-1, Fas 45kD TNFRSF lymph (high upon activation), mono, neutrophils FasL (CD178) receptor, apoptosis DX2
CD96 TACTILE 160kD IgSF NK, Tact adhesion of activated T and NK
CD97 74, 80, 90kD TM7SF Bact and Tact, mono, gran
CD98 4F2 80, 40kD T, B, NK, gran, all human cell lines cellular activation
CD99 MIC2, E2 32kD leukocytes T cell activation, adhesion 3B2/TA8
CD99R E2 32kD T, NK, myeloid cells isoform of CD99
CD100 150kD hematopoietic cells except immature bone marrow cells, RBC and platelets cell adhesion, cellular activation
CD101 V7, p126 120kD IgSF mono, gran, DC, Tact T cell activation
CD102 ICAM-2 55-65kD IgSF lymph, mono, platelets, endoth binds CD11a / CD18, costimulation
CD103 HML-1, alpha6, integrin alphaE 150, 25kD Integrin family intraepithelial lymph, lymph subset, activated lymph with integrin beta7, binds E-cadherin, lymph homing/retention B-Ly7
CD104 beta4 integrin 220kD Integrin family epith, Schwann cells, keratinocytes, some tumor cells with integrin alpha6 (CD49f), cell adhesion, differentiation, metastasis
CD105 Endoglin 95kD homodimer endoth, bone marrow subset, activated mac cellular response to TGF-beta1 SN6
CD106 VCAM-1 110kD IgSF activated endoth, FDC VLA-4 (CD49d / CD29) receptor, leukocyte adhesion, migration, costimulation STA
CD107a LAMP-1 110kD activated platelets, T, endoth, metastatic tumors a lysosomal membrane protein eBioH4A3 (H4A3)
CD107b LAMP-2 120kD activated platelets, T, endoth, metastatic tumors a lysosomal membrane protein eBioH4B4 (H4B4)
CD108 80kD erythrocytes, lymphoblasts, resting lymphlow
CD109 170kD Tact and platelets, CD34+ subset, endoth
CD110 MPL, TPO-R 82-84kD CRSF megakaryocytes, platelets, some CD34+ stem cellslow thrombopoietin receptor, megakaryocyte progenitor cell growth / differentiation
CD111 PRR1, Nectin-1 64-72kD IgSF stem cell subset, mac, neutrophils
CD112 PRR2, Nectin-2 64-72kD IgSF mono, neutrophils, CD34+ subset, megakaryocytes, endoth, epith intercellular adhesion
CD113 PVRL3, Nectin3 83kD IgSF testis, placenta adhesion molecule that interacts with afadin
CD114 G-CSFR 95, 139kD CRSF myeloid progenitors, endoth myeloid differentiation / proliferation
CD115 M-CSFR, c-fms 150kD IgSF, RTK family mono, mac, monocytic progenitors CSF-1R, monocytic differentiation / proliferation 12-3A3-1B10
CD116 GM-CSFRalpha 70-85kD CRSF mono, gran, DC, endoth with common beta, myeloid differentiation / proliferation 4H1
CD117 c-kit, SCFR 145kD IgSF, RTK family hematopoietic progenitors, mast cells SCF receptor, hematopoietic progenitor development / differentiation YB5.B8
CD118 LIFR, gp190 190kD Type I CRSF & secreted forms epithelial cells in adult and embryo membrane-bound involved in signal transduction, soluble form inhibits activity of LIF
CD119 IFNgammaR 90-100kD mac, mono, B, T, NK, neutrophils, endoth IFN-gamma Ralpha, with IFN-gamma AF-1, host defense
  • CD120a
TNFR-I 50-60kD TNFRSF hematopoietic, non-hematopoietic cells receptor for both TNF-alpha and TNF-beta
CD120b TNFR-II 75-85kD TNFRSF hematopoietic, non-hematopoietic cells receptor for both TNF-alpha and TNF-beta
CD121a IL-1R type I 80kD IgSF dimly expressed on many cells binds IL-1alpha and IL-1beta, IL-1 signaling
CD121b IL-1R, type II 60-70kD IgSF B, mac, mono, T subset binds IL-1alpha and IL-1beta, negative signals
CD122 IL-2Rbeta 75kD CRSF NK, T, B, mono IL-2Rbeta and IL-15Rbeta, signal transduction
CD123 IL-3R 70kD CRSF lymph subset, basophils, hematopoietic progenitors, mac, DC, megakaryocytes IL-3Ralpha, with CDw131 6H6
CD124 IL-4R 140kD CRSF lymphlow, mono, hematopoietic precursors, .broblast, epith IL-4Ralpha, with CD132 or IL-13Ralpha, T cell growth / differentiation X2/45-12
CD125 IL-5R 60kD CRSF eosinophils, basophils IL-5Ralpha, with CDw131
CD126 IL-6R 80kD IgSF, CRSF Bact and plasma cells, most leukocyteslow, fibroblasts IL-6Ralpha, with CD130
CD127 IL-7R 65-75kD CRSF T, pro-B IL-7Ralpha, with CD132, B and T cell development eBioRDR5
CD128 see CD181 & CD182
CD130 IL-6Rbeta, gp130 130kD CRSF Bact and plasma cells, most leukocyteslow, endoth IL-6Rbeta, IL-6, IL-11, LIF, CNF signals
CD131 IL-3R common beta 95-120kD CRSF mono, gran, early B with alpha subunits of IL-3R, IL-5R, and GM-CSFR, signal transduction 1C1
CD132 Common gamma 64kD CRSF T, B, NK, mono, gran subunit of IL-2R, IL-4R, IL-7R, IL-9R, and IL-15R, signal transduction mAb (please inquire)
CD133 AC133, prominin-like 1 120kD TM5SF hematopoietic stem cell subset, epith, endoth
CD134 OX-40 48-50kD TNFRSF Tact T cell activation, differentiation, apoptosis ACT35
CD135 Flt3/Flk2 130-150kD RTK family myelomonocytic, primitive B progenitors tyrosine kinase, binds FLT3 ligand, early lymph development BV10A4H2
CD136 MSP-R, RON 180kD RTK family epith, CNS, PNS, hematopoietic subset migration, morphological change and proliferation of different target cells
CD137 4-1BB 30kD TNFRSF Tact T costimulation
CD138 Syndecan-1 80-150kD Syndecan family plasma cells, pre-B, basolateral surface of epith, meurons receptor for ECM, cell morphology DL-101
CD139 228kD B, mono, gran, erythrocyteslow
CD140a PDGFRalpha 180kD RTK family fibroblasts, smooth muscle & glial cells, chondrocytes binds PDGF A and B
CD140b PDGFRbeta 180kD RTK family fibroblasts, smooth muscle & glial cells, chondrocytes binds PDGF B
CD141 Thrombomodulin 100kD C-type lectin mono, neutrophils, endoth, smooth muscle cells initiation of protein C anticoagulant signal
CD142 Tissue Factor 45kD mono, endoth, keratinocytes, epith binds clotting factor VIIa, initiator of clotting
CD143 ACE 170kD endoth, epith, neurons, fibroblasts, activated mac angiotensin converting enzyme, angiotensin II & bradykinin metabolism
CD144 VE-Cadherin, Cadherin-5 130kD Cadherin family endoth adhesion, cell-cell interaction 16B1
CD145 110, 90kD endoth, some stromal cells
CD146 MUC18, S-endo 113-118kD IgSF endoth, melanomas, FDC, Tact adhesion
CD147 Neurothelin, basoglin IgSF leukocytes, erythrocytes, platelets, endoth adhesion
CD148 HPTP-eta 240-260kD gran, mono, DC, T (high upon activation) tyrosine phosphatase R Type III
CD150 SLAM 75-95kD IgSF T subset (high upon activation), B, DC, endoth costimulation, proliferation, Ig production, measles virus receptor A12 (7D4)
CD151 PETA-3 32kD endoth, megakaryocytes, platelets, epith cell adhesion mAb (please inquire)
CD152 CTLA-4 33kD IgSF Tact and B CD80 and CD86 receptor, negative regulation of T cell costimulation 14D3
CD153 CD30L 40kD TNFSF neutrophils, B, Tact and mac CD30 ligand, T costimulation
CD154 CD40L, gp39, TRAP 32-39kD TNFSF Tact CD40 ligand, B and DC costimulation 24-31
CD155 PVR 80-90kD IgSF mono, mac, CD34+ thymocytes Polio virus receptor (PVR)
CD156a ADAM8 69kD neutrophils, mono leukocyte extravasation
CD156b TACE / ADAM 17 100kD broad cleaves membrane proteins (TNF, TGFalpha) to generate soluble forms
CD156c ADAM10 98kD Peptidase M12B family lymphoid organs, peripheral blood leukocyte, cartilage, chondrocytes and fetal liver proteolytic cleavage of cell-surface molecules including Notch, TNF-alpha, APP and ephrin-A2 polyclonal
CD157 BST-1 42-45kD gran, mono, B progenitors, endoth ADP-ribosyl-cyclic ADP-ribose hydrolase activities, pre-B cell growth eBioSY11B5 (SY11B5)
CD158a p58.1 50-58kD IgSF, KIR family NK subset, T subset inhibition of NK cell cytolytic activity, MHC class-I specific NK receptor
CD158b p58.2 50-58kD IgSF, KIR family NK subset, T subset inhibition of NK cell cytolytic activity, MHC class-I specific NK receptor
CD159a NKG2A 43kD T subset, NK with CD94, NK cell receptor
CD159c NKG2C 40kD Type II C-Type Lectin NK with MHC class I HLA-E molecules, forms heterodimer with CD94
CD160 BY55 27kD IgSF NK subset, T subset costimulation
CD161 NKR-P1A 40kD C-type lectin T subset, NK NK cell-mediated cytotoxicity
CD162 PSGL-1 120kD Mucin family mono, gran, most lymph CD62P, CD62L ligand, adhesion, rolling
CD162R PEN-5 CHO NK subset
CD163 130kD Scavenger receptor SF mono, mac eBioGHI/61 (GHI/61)
CD164 MGC-24 80kD epith, mono, lymphlow, bone marrow stromal cells, CD34+ erythroid progenitors hematopoietic progenitor cell-stromal cell interaction
CD165 AD2, gp37 42kD lymph subset, mono, immature thymocytes, platelets adhesion, thymocyte-thymic epith interaction
CD166 ALCAM 105kD IgSF neurons, mono, epith, fibroblasts, Tact CD6 ligand, adhesion
CD167a DDR1 120kD RTK family epith, myoblasts tyrosine kinase, adhesion to collagen
CD168 RHAMM 84-88kD mono, T subset, thymocyte subset, intracellularly in breast cancer cells adhesion, tumor migration, metastasis
CD169 sialoadhesin, Siglec-1 185kD IgSF, sialoadhesins tissue mac subset adhesion, cell-cell and cell-matrix interactions, binds CD227 on breast cancer cells and CD43 on T cells
CD170 Siglec-5, CD33-like2 140kD IgSF, sialoadhesins Mac subset, neutrophils adhesion
CD171 L1 200-210kD IgSF CNS, PNS, glial cells, mono, T subset, B, DC, several human tumor cells kidney morphogenesis, lymph node architecture, T costimulation, neurohistogenesis, homotypic interaction, binds CD9, CD24, CD56, CD142, CD166, integrins
CD172a SIRPgamma 110kD mono, T subset, stem cells adhesion, complex with CD47
CD172b SIRPbeta, SIRB1 50kD IgSF mono and DC negative regulation of RTK-coupled signaling
CD172g SIRPgamma, SIRPB2 45-50kD IgSF, ASV mRNA: liver and at lower levels in many tissues binds CD47
CD173 Blood group H type 2 CHO erythrocytes, stem cell subset, platelets
CD174 Lewis Y CHO stem cells subset, epith
CD175 Tn CHO stem cells subset
CD175s Sialyl-Tn CHO erythroblasts
CD176 Thomson Friedrenreich Ag CHO stem cell subset
CD177 NB1 56-62kD neutrophil subset
CD178 FasL, CD95L 38-42kD TNFSF Tact, testis CD95 ligand, apoptosis, immune privilege, soluble form in serum NOK-1
CD179a V pre B 16-18kD IgSF Pro- and Pre-B B cell differentiation / signaling, with IgM
CD179b Lambda 5 22kD IgSF Pro- and Pre-B B cell differentiation / signaling, with IgM
CD180 RP-105 95-105kD LRRF, TLR family B subset, mono, DC B cell activation, LPS signaling, with MD-1 MHR73-11
CD181 CXCR1, IL-8RA 39kD GPCR1 family neutrophils, basophils, NK, T subset, mono binding of IL-8 induces chemotaxis of neutrophils mAb (please inquire)
CD182 CXCR2, IL-8RB 40kD GPCR1 family neutrophils, basophils, NK, T subset, mono binding of IL-8 induces chemotaxis of neutrophils mAb (please inquire)
CD183 CXCR3 40kD TM7SF eosinophils, Tact and NK, GM-CSF activated CD34+ progenitors IP-10 , Mig and I-TAC receptor, T cell recruitment to inflammatory sites, enhancement of Th1 response
CD184 CXCR4, fusin 45kD TM7SF B, DC, T subset, mono, endoth SDF-1 receptor, X4 HIV-1 coreceptor 12G5
CD185 CXCR5, BLR1 45kD GPCR1 family mature B and Burkitt Lymphoma cells with chemokine BLC, possible regulatory function in Burkitt Lymphomagenesis and/or B differentiation, activation of mature B
CD186 CXCR6, BONZO 40kD GPCR1 family Tact receptor for CXCL16 and coreceptor for SIV, strains of HIV-2 and m-tropic HIV-1 polyclonal
CD191 CCR1, MIP-1alphaR, RANTES-R 39kD GPCR1 family T, mono, stem cell subset binds C-C type chemokines and transduces signal by increasing intracellular calcium ion levels
CD192 CCR2, MCP-1-R 40kD GPCR1 family activated NK and mononuclear phagocytes, T subset, B, endoth binds MCP-1, MCP-3 & MCP-4, alternative coreceptor with CD4 for HIV-1 infection
CD193 CCR3, CKR3 45kD GPCR1 family eosinophils, lower expression in neutrophils and mono, T subset binds eotaxin, eotaxin-3, MCP-3, MCP-4, RANTES & MIP-1delta, alternative coreceptor with CD4 for HIV-1 infectiongg mAb (please inquire)
CD195 CCR5 45kD mono, T subset MIP-1alpha, MIP-1beta and RANTES receptor, R5 HIV-1 coreceptor eBioT21/8 (T21/8)
CD196 CCR6, LARC receptor, DRY6 45kD GPCR1 family T subset, B, DC subset binds MIP-3alpha/LARC
CD197 CCR7 45kD T subset, DC Subset 6Ckine and MIP-2beta receptor CCR7.6B3
CD198 CCR8, GPRCY6, TER1 50kD GPCR1 family T, high expression in Th2, NK, mono allergic inflammation, alternative coreceptor with CD4 for HIV-1 infection polyclonal
CD199 CCR9, GPR-9-6 43kD GPCR1 family subset of memory T, lamina propria mononuclear cells binds SCYA25/TECK, alternative coreceptor with CD4 for HIV-1 infection
CD200 OX-2 45-50kD thymocytes, endoth, B, Tact inhibition of immune response
CD201 EPC-R 50kD endoth subset activated protein C receptor
CD202b Tie2, Tek 150kD RTK family stem cells, endoth angiopoietin-1 receptor
CD203c NPP3 / PDNP3, ENpp1, PD-1b 130-150kD type II TM basophils, mast cells, glioma cells, megakaryocytes ectoenzyme, binding to and clearance of extracellular nucleotides
CD204 Macrophage scavenger-R 220kD mac endocytosis of macromolecules
CD205 DEC-205 205kD DC, thymic epith DC, thymic epith MG38
CD206 macrophage mannose-R 180kD DC subset, mac, mono phagocytosis and pinocytosis of mannose containing molecules
CD207 Langerin 40kD Langerhans cells endocytic receptor
CD208 DC-LAMP 70-90kD DCact, interdigitating DC
CD209 DC-SIGN 44kD DC subset ICAM-3 receptor, HIV-1 binding protein eB-h209
CD210 IL-10-R 90-110kD T, B, NK, mono, mac IL-10 receptor, signal transduction
CD212 IL-12-R beta1 100kD Tact and NK binds IL-12 with high affinity, associates with IL-12 receptor beta2
CD213a1 IL-13-R alpha1 65kD B, mono, fibroblasts, endoth binds IL-13 with low affinity, with CD124
CD213a2 IL-13-R alpha2 65kD B, mono binds IL-13 with high affinity
CD217 IL-17-R 120kD broad IL-17 receptor
CD218a IL-18Ralpha, IL-1Rrp 70kD IL-1R family T, NK, DCs binds IL-18, activation of NF-kappaB H44
CD218b IL-18Rbeta, IL18RAP 70kD IL-1R family T, NK and DCs heterodimeric receptor with IL-18Ralpha to enhance IL-18 binding
CD220 Insulin-R 140, 70kD broad insulin receptor
CD221 IGF-1 R 140, 70kD broad binds IGF with high affinity, signaling, cell proliferation/ differentiation
CD222 IGF-II R, mannose-6 phosphate-R 250kD Type I TM broad, 90-95% intracellular adhesion, tumor growth, a receptor for TGFbeta-LAP, plasminogen, proliferin, truncated form (220kD) found in serum
CD223 LAG-3 70kD IgSF Tact and NK an MHC class II ligand mAb (please inquire)
CD224 GGT 27, 68kD leukocytes, stem cells
CD225 Leu-13 17kD broad
CD226 DNAM-1, PTA-1, TLiSA1 65kD IgSF T, NK, mono, platelets, activated HUVEC activation of cell-mediated cytotoxicity, soluble form (50kD) found in normal serum
CD227 MUC1, EMA 300kD Mucin family, type I TM epith, stem cell subset, FDC, mono, B subset, some myelomas adhesion, signaling, binds CD169, CD54, & selectins mAb (please inquire)
CD228 Melanotransferrin 80-95kD stem cells, melanomas
CD229 Ly-9 95, 110kD IgSF T, B adhesion
CD230 Prion protein 35kD broad
CD231 TALLA-1, A15 30-45kD TM4SF T leukemias, neuroblastomas, brain neurons marker for T cell acute lymphoblastic leukemia
CD232 VESP-R 200kD broad
CD233 Band 3, SLC4A1 90kD Anion exchanger family erythrocytes anion exchanger pump, transport of CO2, linking red cell membrane to cytoskeleton
CD234 Duffy, DARC 35-45kD erythrocytes Duffy antigen chemokine receptor
CD235a Glycophorin A 36kD erythrocytes HIR2 (also GA-R2)
CD235ab Glycophorin A/B 20kD erythrocytes mAb (please inquire)
CD235b Glycophorin B 20kD erythrocytes
CD236 Glycophorin C/D 32, 23kD erythrocytes, stem cell subset
CD236R Glycophorin C 32kD erythrocytes, stem cell subset
CD238 Kell 93kD erythrocytes, stem cell subset
CD239 B-CAM 78-85kD erythrocytes, stem cell subset
CD240CE Rh30CE 30-32kD erythrocytes
CD240D Rh30D 30-32kD TM12SF erythrocytes
CD241 RhAg, Rh50 50kD TM12SF erythrocytes complex with CD47, LW, glycophorin B
CD242 ICAM-4 42kD IgSF erythrocytes adhesion, Landsteiner-Wiener blood group
CD243 MDR-1, p170, P-gp 180kD stem cells, small intestine, kidneystem cells, small intestine, kidney ion pump
CD244 2B4 70kD type II TM T subset, mono, basophils, NK NK activation, CD48 ligand eBioDM244
eBioC1.7 (C1.7)
CD245 p220/240 220-240kD T subset
CD246 ALK, Ki-1 80kD anaplastic T cell leukemias, small intestine, testis, brain, not on normal lymph brain development, implicated in ALK lymphomas
CD247 TCRz 16kD RTK family T, NK TCR complex subunit, coupling of antigen recognition to signaling
CD248 TEM1, Endosialin 175kD C-Type Lectin endothelial tissue, stromal fibroblasts tumor progression and angiogenesis
CD249 Aminopeptidase A 160kD Peptidase M1 family epith, endoth renin-angiotensin system
CD252 OX-40Ligand, gp34 34kD TNFSF Bact, cardiac myocytes T costimulation
CD253 TRAIL, Apo-2L, TL2, TNFSF10 TNFSF Tact, many tissues death RIK-2
CD254 TRANCE, RANKL, OPGL 35kD TNFSF lymph node & BM stroma Tact binds OPG and RANK, osteoclast differentiation, enhances DC to stimulate naïve-T proliferation MIH23
CD256 APRIL, TALL-2 16kD TNFSF mono, mac binds TACI & BCMA, B proliferation polyclonal
CD257 BLyS, BAFF, TALL-1 TNFSF monoact, soluble form B cell growth factor & costimulator of Ig production 1D6
CD258 LIGHT, HVEM-L 28kD TNFSF Tact, immature DC binds LTBR, T proliferation, receptor for HVEM
CD261 TRAIL-R1, DR4 57kD TNFRSF Tact, peripheral blood leukocytes contains death domain, apoptosis via FADD & caspase-8 DJR1
CD262 TRAIL-R2, DR5 60kD TNFRSF widely expressed, peripheral blood lymphocytes contains death domain, apoptosis via FADD and caspase-8 DJR2-4
CD263 TRAIL-R3, DcR1, LIT 65kD TNFRSF peripheral blood lymphocytes receptor for TRAIL but lacks death domain DJR3
CD265 RANK, TRANCE-R, ODFR 97kD TNFRSF broad expression binds TRANCE, osteoclastogenesis, T-DC interactions 9A725
CD266 TWEAK-R, FGF-inducible 14 14kD TNFRSF heart, placenta and kidney, HUVEC TWEAK receptor, cell-matrix interactions and endoth growth and migration ITEM-1
CD267 TACI, TNFR SF13B B, Tact binds BAFF & APRIL 11H3
CD268 BAFFR, TR13C 25kD TNFRSF B binds BLyS, mature B survival 8A7
CD269 BCMA, TNFRSF13B 20kD TNFRSF mature B (membrane and perinuclear) APRIL & BAFF receptor, B survival & proliferation
CD271 NGFR, p75 (NTR) 45kD TNFRSF neurons (schwann cells, growing neurites), BM mesencymal cells NGF, BDNF, NT-3, & NT-4 receptor, tumor suppressor, cell survival and death
CD272 BTLA 33kD IgSF Tact, B , remains on Th1 HVEM receptor, inhibitory response MIH26
CD273 B7DC, PD-L2, PDCD1L2 25kD IgSF DC subset, mono, mac PD-1 receptor, costimulation or suppression of T proliferation MIH18
CD274 B7-H1, PD-L1 33kD IgSF leukocytes, broad PD-1 receptor, costimulation of lymphocytes MIH1
CD275 B7-H2, ICOSL, B7-RP1, GL50 60kD B7 Family B, DC, mono costimulation, cytokine production eBioMIH39
CD276 B7-H3 40-45kD B7 Family, ASV in vitro cultured DC and mono, Tact, mammary tissue costimulation, T activation M3.2D7
CD277 BT3.1, butyrophilin SF3 A1, BTF5 56kD B7/BT family, ASV T, B, NK, mono, DC, endoth, CD34+ cells, tumor cell lines T activation eBioBT3.1 (20.1, BT3.1)
CD278 ICOS, AILIM 55-60kD CD28 family Tact, Th2 binds ICOS-L, T costimulation ISA-3
CD279 PD1, SLEB2 55kD Tact and Bact B7-H1 & B7-DC receptor, autoimmune disease and peripheral tolerance J116
CD280 ENDO180, UPARAP 180kD C-type lectin SF chondrocytes, fibroblasts, endothelial, mac mannose receptor, collagen matrix remodeling and endocytic recycling
CD281 TLR1 90kD TLR family low levels in PBMC, mono and possibly DC innate immunity, with TLR2 GD2.F4
CD282 TLR2 90kD TLR family mono, neutrophil, upregulated in mac binds dsRNA, response to bacterial lipoproteins, innate immunity TL2.1
CD283 TLR3 100kD TLR family, ASV derived moDC (may be intracellular) binds dsRNA, innate immunity TLR3.7
CD284 TLR4 100kD TLR family, ASV PBMC (weak in mono, immature DC & neutro) binds LPS, innate immunity HTA125
CD289 TLR9 120kD TLR family pDC (intracellular) binds CpG-DNA, innate immunity eB72-1665
CD292 BMPR1A, ALK3 57kD Type I bone progenitor BMP 2 & 4 receptor, bone development
CD293 BMPR1B, ALK6 57kD Type I, ASV bone progenitor BMP receptor, bone development
CD294 CRTH2. GPR44 55-70kD GPCR-7TM Th2, eosinophils, basophils binds prostaglandin D2, stimulatory effects on Th2, allergic inflammation
CD295 LeptinR, LEPR 132kD Type I cytokine-like receptor broad adipose metabolism, immune dysfunction in obesity
CD296 ART1, RT6, ART2 37kD ADP- ribosyltransferase heart and skeletal muscle, peripheral T, NK subset modifies integrins during differentiation, ADP ribosylation of target proteins
CD297 ART4, dombrock blood group 38kD ADP- ribosyltransferase erythroid, monoact ADP ribosylation of target proteins
CD298 Na+/K+-ATPase beta3 subunit 52kD broad transport sodium & potassium ions across membrane
CD299 DC-SIGN-related, LSIGN, DC-SIGN2 45kD Type II, similar to CD209, ASV endothelial subset binds ICAM3, HIV-1 gp120, coreceptor with DC-SIGN, HIV infection
CD300a CMRF35H, IRC1, IRp60 60kD IgSF, ASV NK, mono, neutrophils, T and B subset and lymphocytic cell lines, AML unknown
CD300c CMRF35A, LIR IgSF mono, neutrophils, monocytic cell lines, B & T subsets unknown
CD300e CMRF35L IgSF CMRF family unknown
CD301 MGL, HML 38kD C type lectin SF, ASV immature DC binds Tn antigen, uptake of glycosylated antigens
CD302 DCL1, BIMLEC 19-28kD Type I TM C-type lectin receptor some myeloid and Hodgkin's cell lines a fusion protein in Hodgkin's lymphoma with DEC-205
CD303 BDCA2, HECL 38kD C-type lectin SF ASV plasmacytoid dendritic cells inhibit IFN-alpha production
CD304 BDCA4, neuropilin 1 130kD semaphorin family neurons, CD4+/CD25+ Treg, DC, endothelial and tumor cells interacts with VEGF165 & semaphorins, co-receptor with plexin, axonal guidance, angiogenesis, cell survival, migration
CD305 LAIR1 32-40kD IgSF, ASV NK, B, T, mono inhibitory receptor on NK and T cells
CD306 LAIR2 IgSF, ASV unknown soluble, mucosal tolerance
CD307 IRTA2 55-105kD IgSF (Fc receptor), ASV B subset, B lymphoma B cell development, translocation in some lymphomas
CD309 VEGFR2, KDR 230kD Type III TM tyr kinase endothelial, angiogenic precursor cells, hemangioblast binds VEGF, regulates adhesion and cell signaling
CD312 EMR2 90kD EGFR-7TM ASV mono, mac, moDC, granslow cell adhesion and migration for phagocytosis
CD314 NKG2D, KLR 42kD Type II lectin-like receptor NK, CD8+ activated, NK1.1+ T, some myeloid cells binds MHC class I, MICA, MICB, Rae1 & ULBP4, activates cytolysis and cytokine production, costimulation 1D11
CD315 CD9P1, SMAP6, FPRP, PTGFRN 135kD IgSF B subset, monoact with CD81 and CD9
CD316 EWI2, PGRL, CD81P3, KASP 63-75kD IgSF8 B, T cells, low on NK cells with CD81 & CD9; involved in cell migration
CD317 BST2, HM1.24 30-36kD Type II B, T, NK, mono, DC, fibroblast cell line, myeloma pre-B cell growth, overexpressed in multiple myeloma
CD318 CDCP1, SIMA135 135kD Type I, ASV HSC (subset of CD34+), tumors cell adhesion with ECM
CD319 CRACC, SLAMF7 66kD Ig TM T, B and DC subset, NK, upregulated in DC regulate T and NK cells
CD320 8D6A, 8D6 30kD LDL receptor follicular DC, germinal centers B proliferation, tumor formation
CD321 JAM1, F11 receptor 35kD IgSF, Type I, ASV platelet receptor, epithelia and endothelial, platelets tight junctions
CD322 JAM2, VE-JAM 43kD IgSF HEV, other endoth cell adhesion, lymphocyte homing to secondary lymphoid organs
CD324 E-Cadherin, Uvomorulin 120kD cadherin SF non-neural epith cell adhesion, homotypic interaction & binds alphaE/beta7
CD325 N-Cadherin, NCAD 140kD cadherin SF brain, skeletal and cardiac muscle cell adhesion, neuronal recognition
CD326 Ep-CAM, Ly74 35-40kD most epith cell membranes growth factor receptor?
CD327 SIGLEC6 IgSF placenta, spleen, B . sialic-acid dependent adhesion, membrane- bound & secreted forms
CD328 SIGLEC7, AIRM-1 75kD IgSF resting and activated NK, placenta, liver, spleen, lower in gran & mono sialic-acid dependent adhesion, inhibit NK activation, hemopoiesis
CD329 SIGLEC9 IgSF neutrophils and mono sialic-acid dependent adhesion molecule
CD331 FGFR1, Fms-like tyrosine kinase-2, KAL2, N-SAM 30kD TM tyr kinase fibroblasts, epithelial binds FGF, high affinity receptor for fibroblast growth factors
CD332 FGFR2, BEK, KGFR 115-135kD TM RTK family fibroblasts, epithelial binds FGF, high affinity receptor for fibroblast growth factors
CD333 FGFR3, ACH, CEK2 115kD TM RTK family fibroblasts, epithelial binds FGF, high affinity receptor for fibroblast growth factors
CD334 FGFR4, JTK2, TKF 110kD TM RTK family fibroblasts, epithelial binds FGF, high affinity receptor for fibroblast growth factors
CD335 NKp46, Ly-94 homolog 46kD IgSF NK activates NK cells upon non-MHC ligand binding
CD336 NKp44, Ly-95 homolog 44kD IgSF NK activates NK cells upon non-MHC ligand binding
CD337 NKp30, Ly117 30kD IgSF NK activates NK cells upon non-MHC ligand binding
CD338 ABCG2, BCRP, Bcrp1, MXR 73kD GPCR 7TM stem cell subset (side population) multi-drug resistance transporter 5D3
CD339 Jagged-1, JAG1, JAGL1, hJ1 135kD EGF TM stromal cells, epithelial, AML binds Notch, hematopoiesis