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Application

FC : Flow Cytometry, Intracellular Staining/Flow Cytometry

ELISA : ELISA, ELISPOT, Multiplexing Immunoassays

ICC : Immunocytochemistry

IHC : Immunohistochemistry, Immunofluorescence, Microscopy, Imaging, In Vivo Imaging

FA : Functional Assays, Bioassays, Neutralization, Depletion Studies, Biomolecule Conjugation

WB : Immunoprecipitation, Western Blotting

Human IL-18 Matched Antibody Pairs

製品情報

host:  
種交差: Human 
標識: Biotin 
Interleukin-18, Interferon-gamma-inducing factor 
価格
Cat. No. Size Price キャンペーン価格
BMS267/2MST 10 plates ¥86,000  ¥51,600   

Description

Each Module Set is sufficient for ten 96-well microtiter plates and are identical to eBioscience high quality ready-to-use Conventional ELISAs

Formerly called interferon gamma inducing factor (IGIF), IL-18 is a cytokine that plays an important role in the Th1 response, primarily by its ability to induce IFN gamma production in T cells and natural killer cells.
In terms of structure, IL-18 and IL-1 beta share primary amino acid sequences of the so-called "signature sequence" motif and are similarly folded as all beta pleated sheet molecules. Also similar to IL-1 beta, IL- 18 is synthesized as a biologically inactive precursor molecule lacking a signal peptide which requires cleavage into an active, mature molecule by the intracellular cysteine protease called IL-1 beta-converting enzyme (ICE, caspase-1). The activity of the mature IL-18 is closely related to that of IL-1.
The activity of IL-18 is via an IL-18 receptor complex. IL-18 induces gene expression and synthesis of TNF, IL-1, Fas Ligand, and several chemokines. Similar to IL-1, IL-18 participates in both innate and acquired immunity.

Details

Reactivity Human
Components 1 vial (1.1 ml) monoclonal Coating Antibody to human IL-18 (100 ug/ml)
1 vial (55 ul) Biotin-Conjugate anti-human IL-18 monoclonal antibody
1 vial (22 ul) Streptavidin-HRP
1 vial human IL-18 Standard protein lyophilized, 100 ng/ml upon reconstitution
2 vials (50 ml) Sample Diluent
Reported Applications ELISA

Documentation

TDS Link Download TDS

Additional Formats

References

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